Refre was founded 20 years ago.With approximately 5 billion in annual sales, our products have been used regularly by many customers for many years. Almost all our products are made in Japan. We receive orders from numerous customers from bothRefre&＃39;s product lineup consists of over 80 products. Refre is engaged in research-based product development.By thoroughly analyzing raw ingredients and creating multiple prototypes by changing the ingredients and composition balance, a high quality product that meets Refre&＃39;s high standards is created. Refre has a laboratory which runs by emeritus professor Akira Kubo, M.D. He serves as Ministry of Health, Labour and Welfare Pharmaceutical Affairs and Food Sanitation Council expert committee, Japanese Society of Anti-Aging Medicine councilor, Japan society of Health Evaluation and Promotion council member, and the director of The Japanese Clinical Nutrition Association.Product manufacturing is done at factories that have acquired GMP (Good Manufacturing Practice) certification, which is the domestic quality standard, and our products are made under strict quality controls that take environmental and sanitary aspects into account. Refre is a subsidiary of Belluna Co., Ltd, the largest mail order catalog company in Japan.