Schizoderma is the skin care made from natural extracted herbs, schizophyllan mushroom and oyster mushroom. The skin cares from natural extracted have become very popular in the market around the world recently. Thailand has great opportunities in this business because it has various kinds of herbs. It is not just adding values to the Thai herbs, but also bringing new value to innovations in natural skin cares, including Schizoderma. Furthermore, Schizoderma is the only brand in Thailand which has received information on the innovative skin care product made from extracted schizophyllan mushroom and oyster mushroom from The Thailand Institute of Scientific and Technological Research (TISTR) The TISTR has the expertise to conduct research and development on herbal products in Thailand. It has seen the importance of the value-added raw material of mushroom for skin cares. The TISTR had been testing over 10 kinds of mushrooms before it found only two kinds which are the most suitable for the skin, schizophyllum commune Fries., Pleurotus ostreatus (Fr.) Kummer, Pleurotus citrinopileatus Singer.