Supply OEM & ODM Service.We are well known worldwide pharmaceutical store in wholesale of skin care products,we make discount available for bulk buying Tretinoin has been clinically proven to effectively repair photo damaged skin and eliminate acne. Obagi Tretinoin creams are used to treat fine wrinkles, dark spots and rough skin on the face caused by damaging rays of the sun. Tretinoin is the only prescribed treatment for acne and photo damaged skin that works at a cellular level. Obagi Tretinoin penetrates the skin and actually helps to correct the DNA found in the skin cells to correct photodamage.It absorbs quickly.A little goes a long way.Some bottles have 15 SPF (not the one I reviewed though).4. Specification: 20 ml / bottle5. Usage: After thoroughly cleaning the face, take an appropriate amount and smooth it evenly onto the face. This product is effective for 4-6 hours.6. Storage: Please store in the cool and dry place. Keep out of reach of children.7. Cautions:a) Avoid contacting with eyes. If it does, please rinse out immediately.b) If skin has allergic reactions, please stop to use.